Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- abbreviation
small nucleolar RNA
Etymologies
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Examples
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While we do not know if under-accumulation of these snoRNA greatly reduces or abolishes 18S rRNA modifications, we directly questioned whether synthetic lethality between nhp2ins9 and rps15-1 was due to specific absence of these snoRNAs.
PLoS ONE Alerts: New Articles Clément Bellemer et al. 2010
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Positions of Rps15p and rRNA modifications on 18S rRNA, and growth phenotypes for snoRNA-deleted mutants.
PLoS ONE Alerts: New Articles Clément Bellemer et al. 2010
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Such an approach could be extended to identify other specific interactions between ribosomal protein mutants and snoRNA deletions to help understand the role of rRNA modifications, which are still largely unknown.
PLoS ONE Alerts: New Articles Clément Bellemer et al. 2010
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These modifications are catalyzed by small nucleolar ribonucleoparticles (snoRNPs) through specific base-paring between their RNA component (snoRNA) with the surrounding of the position to be modified.
PLoS ONE Alerts: New Articles Clément Bellemer et al. 2010
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Our data thus give hints on the interplay between a ribosomal protein and snoRNA mediated modifications that significantly impair ribosome biogenesis and/or function.
PLoS ONE Alerts: New Articles Clément Bellemer et al. 2010
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Although additive effects were observed for combinations of snoRNA deletions
PLoS ONE Alerts: New Articles Clément Bellemer et al. 2010
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Krek A, Friedländer M, Beitzinger M, Weinmann L, et al. (2008) A human snoRNA with microRNA-like functions.
PLoS ONE Alerts: New Articles Chad J. Creighton et al. 2010
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Since snoRNA ACA45 was found to be processed into a miRNA
PLoS ONE Alerts: New Articles Chad J. Creighton et al. 2010
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Abundance of snoRNAs in nhp2ins9 strains was clearly affected, with very low levels of all the H-ACA snoRNA tested, except snR30 and snR37, even in a snoRNA species listed on the right were probed with relevant oligonucleotides as listed in
PLoS ONE Alerts: New Articles Clément Bellemer et al. 2010
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In this respect, we tried to identify specific synthetic lethality between rps15-1 and a subset of H-ACA snoRNA guides targeted close to the binding site of
PLoS ONE Alerts: New Articles Clément Bellemer et al. 2010
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