Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun biochemistry Any of a group of
proteins that are involved inaxon guidance
Etymologies
Sorry, no etymologies found.
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Examples
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Tzarfaty-Majar V, Lopez-Alemany R, Feinstein Y, Gombau L, Goldshmidt O, et al. (2001) Plasmin-mediated release of the guidance molecule F-spondin from the extracellular matrix.
PLoS ONE Alerts: New Articles Hongqi Xin et al. 2010
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Male C57Bl/6 mice received recombinant adenovirus expressing human R-spondin1 (AdRspo1) or E. coli Lacz (AdLacz), 1-3 days before whole body irradiation (WBI) or abdominal irradiation
PLoS ONE Alerts: New Articles Payel Bhanja et al. 2009
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Male C57Bl/6 mice received recombinant adenovirus expressing human R-spondin1 (AdRspo1) or E. coli Lacz (AdLacz), 1-3 days before whole body irradiation (WBI) or abdominal irradiation
PLoS ONE Alerts: New Articles Payel Bhanja et al. 2009
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Immunoblot analysis showed barely detectable levels of endogenous R-spondin1 in the serum of untreated mice.
PLoS ONE Alerts: New Articles Payel Bhanja et al. 2009
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Nam JS, Turcotte TJ, Smith PF, Choi S, Yoon JK (2006) Mouse cristin/R-spondin family proteins are novel ligands for the Frizzled 8 and LRP6 receptors and activate beta-catenin-dependent gene expression.
PLoS ONE Alerts: New Articles Payel Bhanja et al. 2009
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Semenov MV, Doble B, Woodgett J, et al. (2007) R-spondin1 is a high affinity ligand for LRP6 and induces LRP6 phosphorylation and beta-catenin signaling.
PLoS ONE Alerts: New Articles Payel Bhanja et al. 2009
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Recent reports indicate that the R-spondin proteins activate β-catenin signaling
PLoS ONE Alerts: New Articles Payel Bhanja et al. 2009
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In order to examine the effect of R-spondin1 on tumor growth, AdRspo1 and AdLacZ was administered in the animals having palpable tumor and then exposed to AIR.
PLoS ONE Alerts: New Articles Payel Bhanja et al. 2009
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The R-spondin (roof plate-specific spondin) family of proteins is comprised of novel secreted proteins, which acts as major agonists and modulators of the Wnt-β-catenin signaling pathway
PLoS ONE Alerts: New Articles Payel Bhanja et al. 2009
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Because R-spondin1 (Rspo1) acts as a mitogenic factor for intestinal stem cells, we hypothesized that systemic administration of Rspo1 would amplify the intestinal crypt cells and accelerate the regeneration of the irradiated intestine, thereby, ameliorating RIGS.
PLoS ONE Alerts: New Articles Payel Bhanja et al. 2009
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