from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun medicine A broad-spectrum antibiotic derived from the livers of dogfish


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  • A complex compound produced by sharks, called squalamine, was discovered in 1993 but a new study is exploring its potential use against human viruses. | Top Stories 2011

  • Zasloff discovered the molecule, squalamine, in 1993 in the dogfish shark, a small- to medium-size shark found in the Atlantic, Pacific, and Indian Oceans.

    Yahoo! News: Business - Opinion 2011

  • Yellow fever virus is often used as a surrogate lab test to show possible efficacy against hepatitis C, and the researchers were able to cure yellow fever in hamsters with squalamine.

    Yahoo! News: Business - Opinion 2011

  • Zasloff holds several patents for the use of squalamine and related compounds for the treatment of

    Yahoo! News: Business - Opinion 2011

  • The project began when lead investigator Michael Zasloff, professor of surgery and paediatrics at Georgetown University Medical Centre, sent samples of squalamine to a series of labs around the United States for testing. | Top Stories 2011

  • Researchers tested squalamine - manufactured from the liver of the dogfish shark - in lab dishes and in animal subjects and found it could inhibit or control viral infections, and in some cases appeared to cure animals of their ills. | Top Stories 2011


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