stem-loop

This is a stem-loop, one of the most basic secondary structures that nucleic acids in this case RNA can adopt.

The Techno-Geek Speaks Greek - The Panda's Thumb 2006

The pre-miRNA stem-loop has the possibility of producing two mature miRNAs, one from the plus strand and one from the minus strand (miRNA*).

PLoS ONE Alerts: New Articles Mitchell S. Stark et al. 2010

The first step is the generation, within the nucleus, of stem-loop precursors (pre-miRNAs ~70 nt) by the enzyme Drosha.

PLoS ONE Alerts: New Articles Chad J. Creighton et al. 2010

Total RNA isolated from OVTOKO and HEK293 cell lines was reverse transcribed using the TaqMan® MicroRNA Reverse Transcription Kit from Applied Biosystems (Part Number 4366596) following the manufacturers suggested protocol and specific RT stem-loop primers for mature novel_hsa-bcm-miR-15 sequence and for U6 for an internal control.

PLoS ONE Alerts: New Articles Chad J. Creighton et al. 2010

With their crystal structure model of the Csy4 enzyme bound to its cognate RNA, which features a resolution of 1.8 Angstroms, the Berkeley CRISPR research team has shown that Csy4 makes sequence-specific interactions in the major groove of the CRISPR RNA repeat stem-loop.

PhysOrg.com - latest science and technology news stories 2010

Although several stem-loop structures have been predicted using the 'mfold' program (Zuker, 2003), these are not similar to the

PLoS ONE Alerts: New Articles Hitomi Suzuki et al. 2010

The predicted structures of the engineered pre-amiRNAs incorporated into the pSM155 backbone are shown in Schematic presentation of predicted stem-loop sequences of pSM155-amiR-53Rs.

PLoS ONE Alerts: New Articles Yu-Sin Kim et al. 2010

Although several stem-loop structures have been predicted using the 'mfold' program (Zuker, 2003), these are not similar to the

PLoS ONE Alerts: New Articles Hitomi Suzuki et al. 2010

Dingwall C, Ernberg I, Gait MJ, Green SM, et al. (1990) HIV-1 regulator of virion expression (Rev) protein binds to an RNA stem-loop structure located within the Rev response element region.

PLoS ONE Alerts: New Articles 2009

However, shRNAs are designed as inverted repeats that produce an intramolecular stem-loop structure upon expression.

GEN News Highlights 2009