Definitions
from The American Heritage® Dictionary of the English Language, 5th Edition.
- adjective Of or relating to the calf of the leg.
from The Century Dictionary.
- Of or pertaining to the calf of the leg.
from the GNU version of the Collaborative International Dictionary of English.
- adjective (Anat.) Of or pertaining to the calf of the leg.
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- adjective anatomy Of or pertaining to the
calf of theleg .
Etymologies
from The American Heritage® Dictionary of the English Language, 4th Edition
from Wiktionary, Creative Commons Attribution/Share-Alike License
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Examples
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Picking up a forceps and scalpel, he told de Roon, “Hold down his legs,” and began probing for the sural nerve.
Foreign Influence Brad Thor 2010
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GUPTA: In a five-hour operation, surgeons take sural (ph) nerves from Bill and his mother.
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The sural arteries (aa. surales; inferior muscular arteries) are two large branches, which are distributed to the Gastrocnemius, Soleus, and Plantaris.
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In the lower third of the leg the small saphenous vein is in close relation with the sural nerve, in the upper two-thirds with the medial sural cutaneous nerve.
VII. The Veins. 3d. The Veins of the Lower Extremity, Abdomen, and Pelvis 1918
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In the phase IIb study, SB-509 treatment failed to demonstrate statistically significant improvements from baseline compared with placebo at 180 days in two key measures of nerve regeneration and function -- sural nerve conduction velocity (sNCV) or neuropathy impairment score in the lower limb (NIS-LL).
unknown title 2011
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SB-509 treatment results in statistically significant increases in nerve fiber density, nerve regeneration and an improvement in approvable end-points such as Neuropathy Impairment Score of the Lower Limb (NIS-LL) and sural nerve conduction velocity (sNCV).
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The inclusion criteria for the Phase 2b trial are based upon our accumulated data and include baseline thresholds in measurement, in large sensory nerves as measured by sural nerve connection velocity or NCV in small sensory nerves by Intraepidermal Nerve Fiber Density or IENFD, IENDF and vascular disease severity of DN as measured by baseline ICAM-1 levels in the blood.
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And then final question is regarding that, you said that it was hard to detect a statistical difference in sural nerve conduction velocity change.
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The sural nerve is the first major nerve affected in DN and as this is a double blind study we do not expect to provide interim data and with our historic experience in accrual on to such trials estimate we will have data by the end of 2011.
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NCV in the sural nerve measures the rate of transmission of an electrical signal along the major sensory nerve that runs along the top of the foot.
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