synoviocytes

IL6 was also inhibited by SB-203580, a p38 MAPK inhibitor, in IL1B treated broblast-like synoviocytes

PLoS ONE Alerts: New Articles Gang Wu et al. 2010

G, Suffert G, Semaan N, Juncker T, Frenzel L, et al. (2009) Bruton's tyrosine kinase is involved in mir-346-related regulation of il-18 release by lipopolysaccharide-activated rheumatoid fibroblast-like synoviocytes.

PLoS ONE Alerts: New Articles Gang Wu et al. 2010

Rheumatoid arthritis: Synergistic effects of growth factors drive an RA phenotype in fibroblast-like synoviocytes

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Nutrition 1998 Jul-Aug; 14 (7-8): 599-604 Kontny E et al: The mechanism of taurine choramine inhibition of cytokine production by rheumatoid arthritis fibroblast-like synoviocytes; Arthritis Rheum 2000 Oct,43 (10): 169-77.

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The lining layer is one-to-three cells deep, mainly containing two ultrastructurally distinct cell populations: macrophage-like type A synoviocytes and fibroblast-like type B synoviocytes.

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Synovial membrane and the cartilage are in direct contact with the synovial fluid (SF), a plasma transudate supplemented with saccharide-rich molecules produced by type B synoviocytes.

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Miyazaki T, et al. Involvement of receptor activator of nuclear factor kappaB ligand / osteoclast differentiation factor in osteoclastogenesis from synoviocytes in rheumatoid arthritis.

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V. Mutual antagonism between interferon-gamma and tumor necrosis factor - alpha on HLA-DR expression, proliferation, collagenase production, and granulocyte macrophage colony-stimulating factor production by rheumatoid arthritis synoviocytes.

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We identified FLIP positive cells in early RA cases, both in lining and sublining layers, mainly in the macrophage-like cells and to a lesser extent in fibroblast-like synoviocytes.

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