Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun A small, soluble protein primarily expressed in neural tissue and in certain tumors.

Etymologies

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Examples

  • The finding provides new insight into the fundamentals of Parkinson's disease and the role of an abundant yet mysterious brain protein known as alpha-synuclein, which is believed to help brain cells communicate but may have a more sinister role in the development of neurological diseases.

    University of Florida News 2009

  • The finding provides new insight into the fundamentals of Parkinson's disease and the role of an abundant yet mysterious brain protein known as alpha-synuclein, which is believed to help brain cells communicate but may have a more sinister role in the development of neurological diseases.

    University of Florida News 2009

  • It has been revealed that the Lewy body contains nitrated alpha-synuclein which is prone to [forming aggregates].

    Medlogs - Recent stories 2008

  • It has been revealed that the Lewy body contains nitrated alpha-synuclein which is prone to [forming aggregates].

    Fight Aging! 2008

  • It identified unusual forms of alpha-synuclein, a major component of Lewy bodies, which is a signature characteristic in the brain tissue of

    Xoma and Elan: A Tale of Two Mismanaged Biotech Companies, Part 2 - Seeking Alpha 2011

  • Now J. Timothy Greenamyre, MD, PhD, of the University of Pittsburgh is collaborating with Dr. Li to characterize the alpha-synuclein models 'neurobehavioral deficits, neurochemical alterations, dopaminergic cell loss, neuropathology and molecular features.

    The Earth Times Online Newspaper 2010

  • UC San Diego researchers say too much alpha-synuclein shuts down cell communications, helps cause dementia In diverse neurodegenerative diseases ranging from Parkinson's to Alzheimer's, researchers have long noted accumulations of

    WN.com - Articles related to Healthy Diet Could Slow Or Reverse Early Effects Of Alzheimer's Disease 2010

  • Gregory A. Petsko, DPhil of Brandeis University is investigating shapes that the protein alpha-synuclein may take within cells that can lead to its aggregation into Lewy bodies, a pathological hallmark of Parkinson's disease.

    RedOrbit News - Technology 2010

  • In transgenic mouse models of the Lewy body variant of Alzheimer's, Parkinson's-related alpha-synuclein proteins (green) and the beta-amyloid protein plaques (red) and tau protein tangles (blue) associated with Alzheimer's

    WN.com - Articles related to Adult kids feel sting when mom picks favorites 2010

  • His team successfully used bacterial artificial chromosome (BAC) technology to generate rat lines with five of the most common genetic mutations associated with PD (three alpha-synuclein lines and two LRRK2 lines).

    The Earth Times Online Newspaper 2010

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