Definitions

from The American Heritage® Dictionary of the English Language, 5th Edition.

  • noun Rapid desensitization to a toxic substance produced by inoculation with a series of small doses.
  • noun A rapidly decreasing response to a drug following administration of the initial doses.

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun medicine A rapidly decreasing response to a drug following administration of the initial doses

Etymologies

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Examples

  • If the treatment results regimen can be optimally adapted to the habits are inadequate, the doctor must judge whether of the patient, thereby facilitating his correct the disease is taking a progressive course, execution of the agreed-upon dosing regimen. whether the drug is losing its effect with pro - To do such adaptation effectively, it is essential longed treatment (which pharmacologists call to understand how much forgiveness the pre - 'tachyphylaxis') or whether the cause lies with scribed product allows.

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  • Critics of antidepressants call this “Prozac poop-out,” but mainstream doctors have a much fancier name for it: tachyphylaxis.

    MANUFACTURING DEPRESSION Gary Greenberg 2010

  • Subjectively they may not feel sedated even as larger and larger doses are given over time (known medically as drug tolerance or tachyphylaxis).

    Deepak Chopra: High on Fame: Michael Jackson and Enabling Doctors 2009

  • In medicine, a reduced response to a given medication over time produces tachyphylaxis.

    Technically Speaking, Market Analysis and Theory 2009

  • Prolonged protection without tachyphylaxis following repetitive dosing

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  • Does tachyphylaxis occur in long-term management of scalp sebhorreic dermatitis with pyrithione zinc-based treatments?

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  • Repeated doses of aerosolized NTHi lysate provide prolonged protection against influenza virus without tachyphylaxis.

    PLoS ONE Alerts: New Articles 2009

  • Does tachyphylaxis occur in long-term management of scalp sebhorreic dermatitis with pyrithione zinc-based treatments?

    CosmeticsDesign RSS 2009

  • To test whether tachyphylaxis to the protective effects of the aerosolized NTHi lysate occurs, we challenged mice with influenza in three different conditions: no lysate treatment,

    PLoS ONE Alerts: New Articles 2009

  • When mice were repeatedly exposed to the bacterial lysate, as would be clinically desirable during an influenza epidemic, there was no tachyphylaxis of the induced viral resistance.

    PLoS ONE Alerts: New Articles 2009

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