Definitions

from The American Heritage® Dictionary of the English Language, 5th Edition.

  • noun A drug that is a selective estrogen receptor modulator, C26H29NOS, used in the form of its citrate primarily to treat breast cancer in women whose tumors are estrogen-dependent and to prevent breast cancer in high-risk women.

from the GNU version of the Collaborative International Dictionary of English.

  • noun a chemical compound (C26H29NO) which is non-steroidal but physiogically active as an estrogen antagonist. It is used to treat postmenopausal breast cancer. Chemically it is 1-p-dimethylaminoethoxyphenyl-trans-1,2-diphenyl-but-1-ene. It can be obtained as a white crystalline powder.

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun A nonsteroidal estrogen antagonist used in the treatment of advanced breast cancer

from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.

  • noun an antagonist for estrogen that is used in the treatment of breast cancer

Etymologies

from The American Heritage® Dictionary of the English Language, 4th Edition

[t(rans)– + am(ino)– + alteration of oxy– + alteration of phen(ol).]

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Examples

  • The researchers showed that long-term tamoxifen use increases risk of an drug tamoxifen is a tried-and-true way to lower the chances of developing the most common type of recurrence among breast cancer survivors, but new research suggests it ... drug tamoxifen to reduce the risk of developing a second breast cancer.

    WN.com - Articles related to India industrial output surges 2009

  • In addition to Lupron, I take a daily pill called tamoxifen that is 100% harmful to a fetus.

    Alice Crisci: Too Young for This: Menopause at 32 2009

  • She is also discussing with her doctor the possibility of taking a medication called tamoxifen, which has been shown to cut the chances of breast cancer in women with ADH.

    The Call-Back 2008

  • Then they put you on a drug called tamoxifen, which basically puts you into early menopause.

    CNN Transcript Aug 23, 2006 2006

  • Then they put you on a drug called tamoxifen, which basically puts you into early menopause.

    CNN Transcript Aug 26, 2006 2006

  • Then they put you on a drug called tamoxifen, which basically puts you into early menopause.

    CNN Transcript Dec 25, 2006 2006

  • In the 1970s researchers discovered that the actions of estrogen and other hormones can be blocked chemically by drugs called hormone antagonists, of which the most noteworthy is tamoxifen, which is sold under the trade name Nolvadex.

    Good News and Bad News About Breast Cancer 1996

  • In the 1970s researchers discovered that the actions of estrogen and other hormones can be blocked chemically by drugs called hormone antagonists, of which the most noteworthy is tamoxifen, which is sold under the trade name Nolvadex.

    Good News and Bad News About Breast Cancer 1996

  • Researchers have found that the anti-depressant Seroxat can interfere with tamoxifen, which is prescribed to thousands of breast cancer survivors for five years at a time.

    Home | Mail Online 2010

  • But about half of these cancers do not initially respond to tamoxifen, which is designed to block the hormone from binding to the cell's protein receptor, and many patients that do respond are at risk for developing resistance and cancer relapse.

    THE MEDICAL NEWS Editors 2010

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