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  • noun organic chemistry Any chemical compound, analogous to the amides in which the oxygen atom of the carbonyl group is replaced by sulfur; R-CS-NH2 (and N-derivatives)


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  • Looking over the small SAR table provided, I note that if you switch that thioamide group (the part that the chemists hate the most) to a regular amide, turning the thing into an thiazolidinedione, you lose all the activity.

    In the Pipeline 2010


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