from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun organic chemistry Any
chemical compound, analogous to the amidesin which the oxygenatom of the carbonylgroup is replaced by sulfur; R-CS-NH2 (and N-derivatives)
Sorry, no etymologies found.
Looking over the small SAR table provided, I note that if you switch that thioamide group (the part that the chemists hate the most) to a regular amide, turning the thing into an thiazolidinedione, you lose all the activity.
In the Pipeline 2010