from The Century Dictionary.
- Inducing coagulation.
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- adjective That causes
from Wiktionary, Creative Commons Attribution/Share-Alike License
On the one hand, the “endothelialization” of a stent makes it so that the stent, and especially the disrupted vessel wall under it, was no longer thrombogenic.
Eventually a portion of the endothelialized fat chips off, leaving the highly-thrombogenic changed lipids underneath.
But under the new model of heart disease described above, the reasons for that rapid reduction in flow are clear: by dilating the artery, the balloon can also disrupt the vessel wall, further exposing the blood to the thrombogenic fats and membranes underneath.
This changed fat is extremely thrombogenic - which is to say that a clot forms when normal blood is exposed to it.
In light of the thrombogenic properties of the plaque, it should be obvious these techinques were unsuccessful.
In the course of time, it also became clear, as data from autopsies for people who lived for years with stents became available, that the endothelium that protected the thrombogenic intima from the blood eventually grew through the stent walls.
The researchers also concluded that: "These data may prove useful to women who must decide between tamoxifen and an effective, essentially non-thrombogenic, alternative adjuvant therapy for breast cancer, such as aromatase inhibitors for postmenopausal women and gonadotropin-releasing hormone analogs or oophorectomy for premenopausal women."
These are involved in regulating vasculogenesis and angiogenesis after ischemic injury, interactions of cells with adhesive proteins and blood vessels, proliferation of smooth muscle cells during atherogenesis, metabolism of lipoproteins and non-thrombogenic characteristics of endothelial cells
PLoS ONE Alerts: New Articles Dan E. Arking et al. 2010
The researchers, led by Dr Judy Garber, from the Dana-Farber Cancer Institute in Boston, wrote in The Journal of the National Cancer Institute: "These data may prove useful to women who must decide between tamoxifen and an effective, essentially non-thrombogenic, alternative adjuvant therapy for breast cancer."
"It should not be thrombogenic (meaning it should not aid the clotting of blood) and it should also be able to withstand the blood pressure," he said.
The Economic Times 2010