thymocytes

NGF effect on other spleen cells, such as mononuclear cells [81], and the existence of NGF receptors on thymocytes [82], clearly suggests that the NGF action extends also to cells belonging to a network of enormous functional significance.

Nobel Lecture The Nerve Growth Factor: Thirty-Five Years Later 1986

The CD4 versus CD8 lineage specification of thymocytes is linked to coreceptor expression.

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Figure 4: Defect in the survival of c-Myb-deficient DP thymocytes.

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Mybf/fCd4-Cre (GFP −; right) DP thymocytes (V Fig. 3a).

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Mazr+/+ and Mazr −/− thymocytes was immunoprecipitated with antiserum to MAZR (Ab) or pre-serum (Pre), followed by PCR with primers specific for the

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Mazr+/+ and Mazr −/− thymocytes was immunoprecipitated with antiserum to MAZR (Ab) or pre-serum (Pre), followed by PCR with primers specific for the

Naturejobs - All Jobs Shinya Sakaguchi 2010

Although the mechanisms are still unknown, HLA-A*02 variant in a specific EAE model appeared to increase the negative selection of MBP-reactive CD8+ thymocytes and to decrease the responsiveness of MBP-reactive CD8+ T cells in periphery

PLoS ONE Alerts: New Articles Michele Mishto et al. 2010

Figure 8: DP thymocytes that lack c-Myb are unable to support the development of CD1d deficient

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Shimada H, Ohsaka F, Sakurada T (1988) Adenosine, deoxyadenosine, and deoxyguanosine induce DNA cleavage in mouse thymocytes.

PLoS ONE Alerts: New Articles Ara Parlakian et al. 2010

Far right, Thpok expression in wild-type C57BL/6 CD4SP (4S) and CD8SP (8S) thymocytes.

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