Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • adjective That produces immunological tolerance

Etymologies

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Examples

  • Owen published on the tolerogenic consequences of this placental intermingling of circulation (12).

    Joseph E. Murray - Nobel Lecture 1990

  • Enrichment of T cells with regulatory activity may result in a tolerogenic environment during repopulation; and

    Genzyme Details Market Potential of Alemtuzumab for MS - Yahoo! Finance 2010

  • Michaelsson J, Burt TD, Muench MO, Beckerman KP, et al. (2008) Maternal alloantigens promote the development of tolerogenic fetal regulatory T cells in utero.

    PLoS ONE Alerts: New Articles Karen May et al. 2009

  • Svajger U, Vidmar A, Jeras M (2008) Niflumic acid renders dendritic cells tolerogenic and up-regulates inhibitory molecules ILT3 and ILT4.

    PLoS ONE Alerts: New Articles Devorah Gur-Wahnon et al. 2009

  • However, neither the identity nor the regulatory properties of these tolerogenic lymphocytes have been reported.

    Elites TV 2009

  • The study described herein, identifies the first member of the TGF β/BMP family of stem cell regulators as a novel tolerogenic factor released by NPCs.

    Elites TV 2009

  • The presentations, to be made on March 7 by Argos 'collaborating scientists from the University of Western Ontario, detail positive preclinical data for sCD83 in organ transplantation models, as well its ability to induce and maintain immune tolerance via its generation of tolerogenic dendritic cells (DC) and its direct suppressive effects on T cells and B cells.

    The Earth Times Online Newspaper 2009

  • Expression of ILT3 and ILT4 on DC has been associated with a tolerogenic phenotype which was shown to be crucial to the tolerogenic capacity acquired by DCs

    PLoS ONE Alerts: New Articles Devorah Gur-Wahnon et al. 2009

  • "These abstracts demonstrate that, as a monotherapy, sCD83 is capable of inducing kidney allograft tolerance via the generation of tolerogenic dendritic cells, and that sCD83-mediated B cell suppression contributes to delayed graft rejection," said Dr. Hao Wang of the University of Western Ontario.

    The Earth Times Online Newspaper 2009

  • Albeit their mature-like phenotype these latter cells express the tolerogenic markers ILT3 and ILT4 and possess T cell inhibitory activity.

    PLoS ONE Alerts: New Articles Devorah Gur-Wahnon et al. 2009

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