Definitions
from The American Heritage® Dictionary of the English Language, 5th Edition.
- noun A triplet of nucleotides; a codon.
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun genetics a
codon containing threenucleotides
Etymologies
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Examples
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Also, some genetic disorders are associated with trinucleotide repeats.
Spider Bones Kathy Reichs 2010
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A new class of genetic markers, microsatellite repeats, was identified in 1989 (Litt and Luty 1989; Tautz 1989; Weber and May 1989); because these sets of tandem repeats of short (either dinucleotide, trinucleotide, or tetranucleotide) DNA sequences are more highly polymorphic and detectable by PCR, microsatellites quickly replaced RFLPs as markers of choice for genetic linkage mapping and furnished the STS markers which facilitated the integration of genetic and physical maps.
The Human Genome Project Gannett, Lisa 2008
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Why is the genetic marker for Huntington's disease characterized by an excess of trinucleotide repeats?
Of Foxes and Fundamentalists RICHARD 2005
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Why is the genetic marker for Huntington's disease characterized by an excess of trinucleotide repeats?
Archive 2005-09-01 RICHARD 2005
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McCurrach ME, Harley HG, Buckler AJ, Church D, et al. (1992) Molecular basis of myotonic dystrophy: expansion of a trinucleotide (CTG) repeat at the
PLoS ONE Alerts: New Articles Anna Matynia et al. 2010
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The disease is caused by a trinucleotide repeat expansion situated in the 3′UTR of the
PLoS ONE Alerts: New Articles Anna Matynia et al. 2010
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Forsdyke D (1995) Relative roles of primary sequence and (G+C) % in determining the hierarchy of frequencies of complementary trinucleotide pairs in DNAs of different species.
PLoS ONE Alerts: New Articles Hong-Da Chen et al. 2010
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DMPK gene, located immediately 5′ of the SIX5 gene but the core of the biochemical defect is sequestration of MBNL1 by the expanded trinucleotide repeat RNA in nuclear foci.
PLoS ONE Alerts: New Articles Anna Matynia et al. 2010
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Six5 −/− and Dmpk −/− mice, there is no trinucleotide repeat, these mutants can be used to differentiate between the direct effect of a gene and the effect of impairing the function of other proteins with which they interact.
PLoS ONE Alerts: New Articles Anna Matynia et al. 2010
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McCurrach M, Schalling M, Housman D, Singer RH (1995) Foci of trinucleotide repeat transcripts in nuclei of myotonic dystrophy cells and tissues.
PLoS ONE Alerts: New Articles Anna Matynia et al. 2010
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