tubulogenesis

As a member of the BAR domain superfamily, the tubulogenesis membrane scaffolding protein BIN1 (Amphiphysin 2) is known to induce membrane invagination

PLoS Biology: New Articles Ting-Ting Hong et al. 2010

CC-PLA2s also impaired in vitro human brain microvascular endothelial cell tubulogenesis on Matrigel and showed antiangiogenic activity in vivo in chicken chorioallantoic membrane assay.

Naturejobs - All Jobs Raoudha Kessentini-Zouari 2010

PLCγ1 is necessary for FGF-2-induced tubulogenesis in vitro

PLoS ONE Alerts: New Articles Tania Maffucci et al. 2009

Several lines of evidence indicate that PLCγ1 plays a critical role in angiogenesis, especially in VEGF signalling with data suggesting a role for this enzyme in mediating VEGF-induced cell proliferation and others revealing a role for PLCγ1 in stimulating VEGF-induced differentiation and tubulogenesis

PLoS ONE Alerts: New Articles Tania Maffucci et al. 2009

This process is the result of distinct intracellular events (cell proliferation, apoptosis, migration) and our data indicate that the role of PLCγ1 in tubulogenesis is associated with its role in cell migration.

PLoS ONE Alerts: New Articles Tania Maffucci et al. 2009

These data elucidate the role of PLCγ1 in FGF-2 signalling in HUVECs demonstrating its key role in FGF-2-dependent tubulogenesis.

PLoS ONE Alerts: New Articles Tania Maffucci et al. 2009

In an effort to define the mechanism of PLCγ1-dependent regulation of EC tubulogenesis we found that activation of a PLCγ1/PKCα pathway is necessary for FGF-2-induced Akt phosphorylation.

PLoS ONE Alerts: New Articles Tania Maffucci et al. 2009

We recently demonstrated that FGF-2-dependent migration and tubulogenesis requires activation of the PI3K target PKB/Akt

PLoS ONE Alerts: New Articles Tania Maffucci et al. 2009

Latz C, Rahimi N (2003) Recruitment and activation of phospholipase Cgamma1 by vascular endothelial growth factor receptor-2 are required for tubulogenesis and differentiation of endothelial cells.

PLoS ONE Alerts: New Articles Tania Maffucci et al. 2009

[56] and we reported that this enzyme is necessary for both FGF-2-induced migration and tubulogenesis in HUVEC

PLoS ONE Alerts: New Articles Tania Maffucci et al. 2009