uncastable

Definitions

adjective That cannot be cast (filled with, or allocated, a theatrical role).
adjective computing, programming That cannot be cast (converted to other data types).
adjective medicine That cannot be set in a cast.
adjective That cannot be used for, or produced through, casting (manufacturing with a mould).

un- +‎ castable

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Pitt, who recently signed on for "Mr. and Mrs. Smith" with Angelina Jolie, will star in a movie called "Chad Schmidt," written by Steve Conrad, in which a young actor moves to L.A. in the 1980s and becomes uncastable because he looks so much like a rival hopeful: Brad Pitt.

NEWSMAKERS 2007
"Very rarely do you find an actor who can really take on the varied complications of this character, which is one of those virtually uncastable Williams parts," Mr. Cromer said.

NYT > Home Page By PATRICK HEALY 2011
Why she’s GOSSIP worthy: Because the original mean girl is virtually uncastable on the big screen and juicy role on GOSSIP GIRL could be a first step back to respectability.

We Re-Cast Misha Barton’s Role on GOSSIP GIRL | the TV addict 2008
They were willing to pay off myself and Bob Butler, the director of the pilot, and Cybill Shepherd, to go away, "because ABC execs said the lead was uncastable, even after Willis had been chosen by Caron.

unknown title 2009
They were willing to pay off myself and Bob Butler, the director of the pilot, and Cybill Shepherd, to go away, "because ABC execs said the lead was uncastable, even after Willis had been chosen by Caron.

unknown title 2009