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Examples
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AstraZeneca's experimental pill called vandetanib has been filed for approval in the U.S. and Europe after data showed the drug delayed progression of a rare type of thyroid cancer, and U.S. regulators have given the medicine a priority review.
Business Watch 2010
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LONDON — An experimental AstraZeneca PLC pill called vandetanib has been filed for approval in the U.S. and Europe after data showed the drug delayed progression of a rare type of thyroid cancer, and U.S. regulators have given the medicine a priority review.
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Astsaturov has started testing a drug called vandetanib -- which simultaneously inhibits EGFR and RET (another protein in the
'Synthetic lethality' strategy improves molecularly targeted cancer therapy 2010
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AstraZeneca wants vandetanib approved in the U.S. for treating patients there with non-operable metastatic medullary thyroid cancer.
Business Watch 2011
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U.S. regulators have postponed by three months a decision on whether to approve AstraZeneca experimental thyroid cancer pill vandetanib, because they need more time to evaluate it, the U.K. drug maker said.
Business Watch 2011
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After an average follow-up of 24 months, 48% of patients on vandetanib continued on the treatment, 37% had their disease get worse, and 15% died.
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Researchers said the patients treated with vandetanib had a 54% reduced risk of progression of thyroid cancer, compared with patients not receiving it.
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The company had proposed selling vandetanib under the brand name Zactima.
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Peter Langmuir, AstraZeneca's executive director of medical science, said the company plans to file for FDA approval of vandetanib to treat medullary thyroid cancer, based on study results it presented Monday at the American Society of Clinical Oncology's annual meeting.
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In the study of 331 patients with advanced medullary thyroid cancer, about 230 received vandetanib and 100 received a placebo.
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