whole-cell

The whole-cell pertussis vaccine was suggested as a cause of brain injury including epilepsy and mental retardation; however, multiple studies have found that while there are more cases of fever-induced seizures, there are not permanent brain injuries.

Global Immunization: Vaccine Coverage is Variable 2010

Neither was found to be causally related to the whole-cell pertussis vaccine.

Global Immunization: Vaccine Coverage is Variable 2010

Before the introduction of whole-cell vaccines, whooping cough was at best an unpleasant passage of childhood, at worst a deadly tragedy.

Whooping cough makes a comeback Arthur Allen 2010

Those whole-cell vaccines, developed in the 1940s, were made by deactivating whole pertussis bacteria.

Whooping cough makes a comeback Arthur Allen 2010

"The acellular vaccines simply aren't as good as the good whole-cell vaccines," says James Cherry of UCLA, who has studied whooping cough for the past 30 years.

Whooping cough makes a comeback Arthur Allen 2010

"The acellular vaccines simply aren't as good as the good whole-cell vaccines," says James Cherry of UCLA, who has studied whooping cough for the past 30 years.

Whooping cough makes a comeback Arthur Allen 2010

Those whole-cell vaccines, developed in the 1940s, were made by deactivating whole pertussis bacteria.

Whooping cough makes a comeback Arthur Allen 2010

The controversy over the whole-cell vaccines began in the late 1970s and never really ended, but they were replaced in the United States by vaccines that instead contained varying amounts and types of purified pertussis proteins.

Whooping cough makes a comeback Arthur Allen 2010

The controversy over the whole-cell vaccines began in the late 1970s and never really ended, but they were replaced in the United States by vaccines that instead contained varying amounts and types of purified pertussis proteins.

Whooping cough makes a comeback Arthur Allen 2010

Before the introduction of whole-cell vaccines, whooping cough was at best an unpleasant passage of childhood, at worst a deadly tragedy.

Whooping cough makes a comeback Arthur Allen 2010