Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun biochemistry A
protein thatmodulates thepermeability oftight junctions betweencells of thewall of thedigestive tract .
Etymologies
from Wiktionary, Creative Commons Attribution/Share-Alike License
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Examples
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Dr. Fasano and his colleagues also have identified a protein called zonulin that makes intestines unusually permeable.
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It was nine years ago that University of Maryland School of Medicine researchers discovered that a mysterious human protein called zonulin played a critical role in celiac disease and other autoimmune disorders, such as multiple sclerosis and diabetes.
THE MEDICAL NEWS 2009
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I’m certainly not an expert on zonulin, which is a protein involved in the tight junctions between intestinal cells.
Hard at work on Orcas Island | The Blog of Michael R. Eades, M.D. 2009
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In people with celiac disease, gluten itself stimulates the release of zonulin.
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Since coeliac disease and even type I diabetes are thought by some to be autoimmune disorders, the integrity of the zonulin may be involved.
Hard at work on Orcas Island | The Blog of Michael R. Eades, M.D. 2009
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One of the toxins from the cholera bacteria attacks zonulin, making the tight junctions break down and causing GI havoc.
Hard at work on Orcas Island | The Blog of Michael R. Eades, M.D. 2009
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That zonulin might be the smoking gun for T1 diabetes and other auto-immune diseases.
Inflammation and diet | The Blog of Michael R. Eades, M.D. 2007
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Gluten, at least, is known for triggering the release of zonulin, which opens up the “tight junctures” and so releases more undigested food into the blood than *should* get there.
Inflammation and diet | The Blog of Michael R. Eades, M.D. 2007
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They have identified zonulin as a molecule in the human body called haptoglobin
Gaea Times (by Simple Thoughts) Breaking News and incisive views 24/7 2009
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"This molecule could be a critical missing piece of the puzzle to lead to a treatment for celiac disease, other autoimmune disorders and allergies and even cancer, all of which are related to an exaggerated production of zonulin/pre-haptoglobin 2 and to the loss of the protective barrier of cells lining the gut and other areas of the body, like the blood brain barrier," says Dr. Fasano.
THE MEDICAL NEWS 2009
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