Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun genetics The complete exon content of an organism or individual

Etymologies

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Examples

  • Thus, as a practical matter, sequencing the exome is a high-value, more affordable alternative to sequencing the entire genome.

    The $1,000 Genome Kevin Davies 2010

  • The first step is to sequence 1 percent of each volunteer's genome, focusing on the so-called exome — the protein-coding regions that, Church suspects, do 90 percent of the work in our DNA.

    How the Personal Genome Project Could Unlock the Mysteries of Life 2008

  • A Yale team led by Murat Gunel has already used partial genome sequencing of the 1.5 percent of the genome, called the exome, that codes for proteins to determine the cause of a mysterious and still unnamed genetic disease that results in severe brain malformations.

    Yahoo! News: Business - Opinion 2012

  • Your genome is the sequence of all your DNA; your exome is a subset of your genome that contains the part of the DNA that codes for the genes.

    unknown title 2011

  • The exome is the portion of the genome that contains genes that code for proteins.

    Yahoo! News: Business - Opinion 2011

  • A Yale team led by Murat Gunel has already used partial genome sequencing of the 1.5 percent of the genome, called the exome, that codes for proteins to determine the cause of a mysterious and still unnamed genetic disease that results in severe brain malformations.

    Reuters: Press Release 2012

  • For the first time, scientists have successfully used a method called exome sequencing to quickly di ...

    THE MEDICAL NEWS Editors 2010

  • In their study, the team used a new type of genomics technology called exome sequencing to find the mutation in the valosin-containing protein VCP gene, which has been described as a molecular "chaperone" aiding various cellular activities such as protein breakdown.

    Yahoo! News: Business - Opinion 2010

  • In their study, the team used a new type of genomics technology called exome sequencing to find the mutation in the valosin-containing protein VCP gene, which has been described as a molecular "chaperone" aiding various cellular activities such as protein breakdown.

    Yahoo! News: Business - Opinion 2010

  • The Sanger Institute (where I work) has formally announced the launch of the UK10K Project, which will sequence the whole genomes of 4,000 people at low coverage, as well as sequencing all of the protein-coding genes (collectively known as the exome) of a further 6,000 people.

    ScienceBlogs Channel : Life Science 2010

Comments

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  • In 2007 (George Church) told me he expected that soon his lab would be able to use the Polonator to sequence the entire human exome, that is, the protein-coding 1 percent of the human genome, for as little as a thousand dollars.
    Misha Angrist, Here is a Human Being: At the Dawn of Personal Genomics (New York: HarperCollins, 2010), ch. 2 (Kindle loc. 342)

    December 17, 2016