Definitions

from The American Heritage® Dictionary of the English Language, 4th Edition

  • n.pl. Informal Pain in the stomach or bowels.

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. Anxiety, fear

from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.

  • n. severe gastroenteritis of unknown etiology; characterized by severe colic and vomiting and diarrhea

Etymologies

Probably alteration (influenced by colic and wobble) of cholera morbus.
(American Heritage® Dictionary of the English Language, Fourth Edition)
Attested 1823, presumably from colic + wobble.[2] Alternative theories are that it derives from colly ("coal dust"), via the putative sense “ill from breathing coal dust,”[1] or that it is a corruption of cholera.[3] The first attestation (a mention, not a usage) is in the 1823 edition of A Classical Dictionary of the Vulgar Tongue.[1] (Wiktionary)

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