Definitions

from The American Heritage® Dictionary of the English Language, 5th Edition.

  • noun A tricyclic antidepressant drug, C9H21NO, used in its hydrochloride form.

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun A psychotropic agent with tricyclic antidepressant and anxiolytic properties.

from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.

  • noun a tricyclic antidepressant (trade names Adapin and Sinequan) with numerous side effects (dry mouth and sedation and gastrointestinal disturbances)

Etymologies

from The American Heritage® Dictionary of the English Language, 4th Edition

[d(ibenz)oxepin(e), tricyclic structural component : di– + benz– + oxepin(e), seven-member ring with one oxygen atom (ox(o)– + (h)ep(ta)– + –ine).]

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Examples

  • The active ingredient in Silenor, doxepin, has been used for years in higher doses as an antidepressant.

    Dawn of A New Sleep Drug? Andrea Petersen 2011

  • If the condition persists, your doctor may recommend either an antihistamine such as diphenhydramine (Benadryl Allergy) or doxepin cream (Zonalon); a nonsteroidal anti-inflammatory ointment or cream such as tacrolimus (Protopic); or a corticosteroid ointment such as hydrocortisone (Cortaid, Cortizone).

    Q&A: Does cat fur and dander cause eczema? 2010

  • If the condition persists, your doctor may recommend either an antihistamine such as diphenhydramine (Benadryl Allergy) or doxepin cream (Zonalon); a nonsteroidal anti-inflammatory ointment or cream such as tacrolimus (Protopic); or a corticosteroid ointment such as hydrocortisone (Cortaid, Cortizone).

    Q&A: Does cat fur and dander cause eczema? 2010

  • The current nightcap, as it were, is 50 mg doxepin, followed in one hour by 10 mg zolpidem this is the non-CR version of Ambien.

    dustbury.com » Snooze on the hour 2008

  • “But I only take the doxepin and flurazepam to sleep and it was about time to wean myself from the Prozac anyway.”

    A Winter Haunting Simmons, Dan 2002

  • Dale turned the light out and went back to sleep, even without his Prozac and flurazepam and doxepin.

    A Winter Haunting Simmons, Dan 2002

  • Silenor, or doxepin, is a low-dose oral prescription drug that is used to treat short and long term insomnia.

    unknown title 2011

  • Lastly, Paladin entered into an exclusive collaboration with Somaxon Pharmaceuticals, Inc. to commercialize Silenor® doxepin for the treatment of insomnia characterized by difficulty with sleep maintenance in Canada, South America and Africa.

    unknown title 2011

  • The drug's active ingredient, doxepin hydrochloride, has been around for decades and was previously used in much higher doses as an anti-depressant.

    Somaxon Pharmaceuticals: Will FDA Approval Ever Pay Off? - Seeking Alpha 2011

  • Somaxon's product Silenor® (doxepin) has been approved by the FDA for the treatment of insomnia characterized by difficulty with sleep maintenance.

    The Earth Times Online Newspaper 2010

Comments

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  • Yet he'd felt a real sadness — the sadness of consummation— hearing a subject who'd struggled for years with anxiety, suicidal guilt, and religious zeal tell him, after the successful tuning of his doxepin dosages, "Doctor, I'm just not sure what I was so upset about, all that time.

    --Richard Powers, 2007, The Echo Maker, p. 190

    November 7, 2008