Definitions
from The American Heritage® Dictionary of the English Language, 5th Edition.
- noun A localized region on the surface of an antigen capable of eliciting an immune response and of combining with a specific antibody to counter that response.
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun biochemistry That part of a
biomolecule (such as aprotein ) that is thetarget of animmune response
from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
- noun the site on the surface of an antigen molecule to which an antibody attaches itself
Etymologies
from The American Heritage® Dictionary of the English Language, 4th Edition
Support
Help support Wordnik (and make this page ad-free) by adopting the word epitope.
Examples
-
This recombinant protein was used since deletion of the internal epitope between amino acids 433 and 447, called epitope 1443, increases the production of neutralizing antibodies in mouse models of infection
PLoS ONE Alerts: New Articles Laura Ratier et al. 2008
-
T cell mimicry and epitope specificity of cross-reactive T cell clones from rheumatic heart disease.
The Autoimmune Epidemic Donna Jackson Nakazawa 2008
-
T cell mimicry and epitope specificity of cross-reactive T cell clones from rheumatic heart disease.
The Autoimmune Epidemic Donna Jackson Nakazawa 2008
-
Taking into account the circulating B cells and calculating the quantity of antibody per immunologically-distinct epitope, the conclusion was that an infant could mount a response to the antigens present in “10 000 vaccines”.
On Thursday, the Legg report will be published along with... 2008
-
Although these features are inconsequential for the use of DsRed as a reporter of gene expression, the usefulness of DsRed as an epitope tag is severely limited.
Archive 2005-10-01 2005
-
Unfortunately, this protein is an obligate tetramer, making it less suitable fur use as an epitope tag than PA-GFP.
Archive 2005-10-01 2005
-
HVTN said the vaccine candidate was a multi-epitope vaccine developed by Epimmune, a San Diego-based pharmaceutical company.
-
The library's diversity is expected to result in antibodies against previously inaccessible target molecules and unique epitope coverage.
-
All cTnI constructs were derived from the full-length rodent sequence and tagged with C-terminal Flag epitope (DYKDDDDK, Sigma) to distinguish the recombinant from the native cTnI; while, the Tm mutants were engineered into the full-length human Tm
PLoS ONE Alerts: New Articles Jennifer Davis et al. 2010
-
G159D cTnC was subcloned into the pDC315 AdMax shuttle vector (Microbix Biosystems Inc.) with and without an HA (Hemagglutinin) epitope tag as previously described
PLoS ONE Alerts: New Articles Jennifer Davis et al. 2010
Comments
Log in or sign up to get involved in the conversation. It's quick and easy.