Definitions
from The American Heritage® Dictionary of the English Language, 5th Edition.
- noun Any of a group of sugar molecules that are freestanding as oligosaccharides or polysaccharides or are combined in conjugates, as in glycoproteins.
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun chemistry Any
polysaccharide oroligosaccharide , epsecially one that is part of aglycoprotein orglycolipid
Etymologies
from The American Heritage® Dictionary of the English Language, 4th Edition
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Examples
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The team also showed that as flu viruses circulate, they develop a kind of shield called a glycan that protects them from the body's immune system.
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The team also showed that as flu viruses circulate, they develop a kind of shield called a glycan that protects them from the body's immune system.
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Loss of GlcNAcT-IVa, or the addition of glycan-ligand mimetics, attenuates Glut-2 cell-surface half-life, provoking endocytosis with redistribution into endosomes and lysosomes.
“I have vision, and the rest of the world wears bifocals.”* | The Blog of Michael R. Eades, M.D. 2006
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The GnT-4a enzyme is required to synthesize a glycan structure that holds the glucose transporter in place at the beta cell surface.
“I have vision, and the rest of the world wears bifocals.”* | The Blog of Michael R. Eades, M.D. 2006
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We show that the murine GlcNAcT-IVa glycosyltransferase is required for Glut-2 residency on the β cell surface by constructing a cell-type- and glycoprotein-specific N-glycan ligand for pancreatic lectin receptors.
“I have vision, and the rest of the world wears bifocals.”* | The Blog of Michael R. Eades, M.D. 2006
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Develop and validate cell based activity methods for protein analysis, glycosylation (glycan isoforms & sialic acid) and heterogeneity ( C & N terminal sequencing, peptide mapping and size exclusion chromatography).
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Dr. Szabo and his colleagues, however, used PCT to accelerate N-linked glycan release by peptides using the enzyme N-Glycosidase F, also known as PNGase F. Membrane proteins represent one of the most appealing targets for cancer detection and therapy.
Science Blog 2010
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Aslam H, Tear G, Casanova J (2005) mummy/cystic encodes an enzyme required for chitin and glycan synthesis, involved in trachea, embryonic cuticle and CNS development-analysis of its role in Drosophila tracheal morphogenesis.
PLoS ONE Alerts: New Articles Michaela Norum et al. 2010
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PA401 is a glycan-binding decoy protein based on human chemokine IL-8 (CXCL8), which has shown potent anti-inflammatory activity in both chronic and acute preclinical models of lung inflammation.
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This antigenic site plays a crucial role in conferring specificity to galactose of the human α2-6 sialylated glycan receptor
PLoS ONE Alerts: New Articles Makoto Kuroda et al. 2010
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