Definitions

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun chemistry, biochemistry A dimer, especially a biologically active one, derived from two or more different monomers

Etymologies

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Examples

  • "We want to identify agents that make ER beta pair with ER alpha, in a structure called a heterodimer, potentially allowing the beta to dampen the alpha activity," says Xu, lead author of the study.

    Health News from Medical News Today 2008

  • SUMO-1 is activated by an E1 activating enzyme (the heterodimer Aos1/Uba2) and is then transferred to the E2 conjugating enzyme (UBC9), and thence to a specific lysine in the target protein by an a E3 ligase.

    PLoS ONE Alerts: New Articles Mara Marongiu et al. 2010

  • Unlike the hepatitis C virus, where the envelope proteins E1 and E2 form a heterodimer for viral entry

    PLoS ONE Alerts: New Articles Yonghui Zhang et al. 2010

  • The two "biomarkers" were the short heterodimer partner and the progesterone receptor.

    Yahoo! News: Business - Opinion 2010

  • Human lysosomal β-hexosaminidase A is a heterodimer composed of

    Naturejobs - All Jobs Kazuhiko Matsuoka 2010

  • Aly binds to the mRNA export receptor Tap: p15 heterodimer that interacts with the FG nucleoporins in the pore channel to move the mRNP through the nuclear pore

    PLoS ONE Alerts: New Articles Jiang Zhu et al. 2010

  • The HIF-1 protein is a heterodimer composed of a constitutively expressed β-subunit (ARNT (aryl hydrocarbon receptor nuclear translocator)) and a hypoxia-inducible α-subunit

    PLoS ONE Alerts: New Articles Nadine Rohwer et al. 2010

  • Whereas most other enveloped viruses use a single viral catalyst called a fusogen, herpes viruses inexplicably require two conserved fusion-machinery components, gB and the heterodimer gH-gL, plus other nonconserved components. gB is a class

    PhysOrg.com - latest science and technology news stories 2010

  • (RXR) agonists, which activate the PPAR/RXR heterodimer, downregulate resistin gene expression in 3T3L1 adipocytes

    PLoS ONE Alerts: New Articles Anil K. Singh et al. 2010

  • DB complexes share global shape properties with standard transient heterodimer complexes, but their accessible surface areas are significantly smaller.

    Elites TV PLoS ONE 2010

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