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neuraminidase love

neuraminidase

Definitions

from The American Heritage® Dictionary of the English Language, 5th Edition.

  • noun A hydrolytic enzyme that removes sialic acid from mucoproteins and is found chiefly in microorganisms of the respiratory and intestinal tracts.

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun biochemistry An antigenic enzyme, found on the surfaces of viruses, that catalyzes the hydrolysis of terminal acylneuraminic residues from oligosaccharides, glycoproteins, and glycolipids

Etymologies

from The American Heritage® Dictionary of the English Language, 4th Edition

[neuramin(ic acid) (neur(o)– + amin(e)) + –id(e) + –ase.]

from Wiktionary, Creative Commons Attribution/Share-Alike License

-ase

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Examples

  • Research suggests neuraminidase, which is a substance needed by the H5N1 virus to reproduce, may be inhibited.

    A long season begins -- and we don't mean football (Jack Bog's Blog) 2009

  • Oseltamivir is known as a neuraminidase inhibitor that does not actually kill swine flu or other influenza viruses directly.

    Doctor Star | SciFi, Fantasy & Horror Collectibles 2009

  • According to various expert epidemiological sources, strains of influenza are becoming progressively resistant to currently available commercial antiviral drugs (including so-called neuraminidase inhibitors) and death rates are expected to increase globally without the development of new effective treatment strategies.

    News 2010

  • Relenza and Tamiflu are known as neuraminidase inhibitors (NIs).

    The Guardian World News 2009

  • According to John Oxford, Professor of Virology at Barts and the London School of Medicine, the drug works by inhibiting chemicals known as neuraminidase enzymes in the virus.

    Home | Mail Online 2009

  • But so far, it remains sensitive to the two drugs known as neuraminidase inhibitors:

    Medlogs - Recent stories 2009

  • Relenza and Tamiflu are known as neuraminidase inhibitors (NIs).

    The Guardian World News 2009

  • According to John Oxford, Professor of Virology at Barts and the London School of Medicine, the drug works by inhibiting chemicals known as neuraminidase enzymes in the virus.

    Home | Mail Online 2009

  • Zinc is a mild to moderate inhibitor of neuraminidase.

    A long season begins -- and we don't mean football (Jack Bog's Blog) 2009

  • Zinc ions have been shown to have a slight inhibitory action on all strains of neuraminidase tested Zinc reduces TNF, IL-1 and IL-8 production Zinc can also turn down TNF, ICAM and other cytokines involved in over reaction to H5N1 and other viruses.

    A long season begins -- and we don't mean football (Jack Bog's Blog) 2009

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Comments

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  • chained_bear commented on the word neuraminidase

    "Meanwhile, the spikes of neuraminidase, the other protuberance that jutted out from the surface of the virus, are performing another function. Electron micrographs show neuraminidase to have a boxlike head extending from a thin stalk, and attached to the head are what look like four identical six-bladed propellers. The neuraminidase breaks up the sialic acid remaining on the cell surface. This destroys the acid's ability to bind to influenza viruses."

    —John M. Barry, The Great Influenza (NY: Penguin Books, 2004), 104

    February 11, 2009