Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- adjective genetics Having a
similar structure indicatingdivergence from a commonancestral gene - adjective metaphorical Having a
similar structure , quality or nature indicatingdivergence or relationship from a common point of origin.
Etymologies
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Examples
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Phylogenitic analysis, homologus/paralogous gene structure/functional relationships are predicated on these simple evolutionary concepts and undergird breakthroughs in understanding mechanisms and pathways of the cell necessary for modern medicine.
Egnorance: The Egotistical Combination of Ignorance and Arrogance - The Panda's Thumb 2007
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Conversely, the reason for the increase in dN/dS in many genes within CNV regions could be attributed to their higher number of paralogous sequences.
PLoS ONE Alerts: New Articles Benjamin Schuster-B�ckler et al. 2010
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Mammals have three Ugt2a and multiple Ugt2b genes genes have orthologs in mice and rats, while the human UGT2B genes display paralogous relationship to those of mouse and rat
PLoS ONE Alerts: New Articles Haiyan Huang et al. 2010
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The subunit, a 400 kDa polypeptide, is a concatenation of eight paralogous functional units.
BioMed Central - Latest articles Bernhard Lieb 2010
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Mammals have three Ugt2a and multiple Ugt2b genes genes have orthologs in mice and rats, while the human UGT2B genes display paralogous relationship to those of mouse and rat
PLoS ONE Alerts: New Articles Haiyan Huang et al. 2010
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The downstream paralogous Ugt5b5p pseudogene does not share any
PLoS ONE Alerts: New Articles Haiyan Huang et al. 2010
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The downstream paralogous Ugt5b5p pseudogene does not share any
PLoS ONE Alerts: New Articles Haiyan Huang et al. 2010
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Vatolin S, Abdullaev Z, Pack SD, Flanagan PT, Custer M, et al. (2005) Conditional expression of the CTCF-paralogous transcriptional factor BORIS in normal cells results in demethylation and derepression of MAGE-A1 and reactivation of other cancer-testis genes.
PLoS ONE Alerts: New Articles Ian M. Smith et al. 2009
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D. discoideum CbfA-like protein, CbfB, share a paralogous domain arrangement that includes the JmjC domain, presumably a chromatin-remodeling activity, and two zinc finger-like
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D. discoideum CbfA and CbfB are paralogous within the JmjC / ZF region, but have completely unrelated carboxy-terminal domains.
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