Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun pharmacology The
molecular framework responsible for adrug 'sbiological activity .
Etymologies
Sorry, no etymologies found.
Support
Help support Wordnik (and make this page ad-free) by adopting the word pharmacophore.
Examples
-
A pharmacophore is a set of structural features in a molecule that is recognized at a receptor site.
Forever Young M.D. Nicholas Perricone 2010
-
As for cinnamic aldehyde, the curcuminoids, and the nitroalkenes, I believe the anticancer activity and other therapeutic benefits of a nitrone spin trap results from the fact that it is a mild electrophile and a Michael acceptor pharmacophore.
Forever Young M.D. Nicholas Perricone 2010
-
When phytonutrients and other molecules that contain the Michael acceptor–like pharmacophore upregulate the transcription factor NRF2, more than a dozen protective anti-inflammatory proteins in the cell are activated.
Forever Young M.D. Nicholas Perricone 2010
-
The paper notes that the MCSS is not necessarily of biochemical relevance, indicating that there is room for pharmacophore like concept in the CDK.
CDK Literature #1 Egon Willighagen 2007
-
The paper notes that the MCSS is not necessarily of biochemical relevance, indicating that there is room for pharmacophore like concept in the CDK.
Archive 2007-01-01 Egon Willighagen 2007
-
At the conference, Addex will disclose a novel oral mGluR4 PAM chemical scaffold with a pharmacophore and structure activity relationship that is completely different from existing molecules in the field.
-
The pharmacophore models may then be use to select compound libraries that are enriched with features desirable for
-
* Design and synthesis of SERCA inhibitors base don the pharmacophore of thapsigargin.
-
* Design and synthesis of SERCA inhibitors base don the pharmacophore of thapsigargin.
-
Subsequently we will derive inverted pharmacophore models for the binding modes observed.
qms commented on the word pharmacophore
We can't do much more than deplore
The tenants our frail bodies store.
I’m glad of the pills
Addressing my ills
With versatile pharmacaphore.
October 27, 2018
bilby commented on the word pharmacophore
*applause*
October 30, 2018
bilby commented on the word pharmacophore
deplorablelimericks.com
October 30, 2018