Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun biochemistry A
chain of severalubiquitin molecules attached to aprotein .
Etymologies
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Examples
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"So now we have two examples showing that these free polyubiquitin chains can activate signaling cascades," said Chen.
HHMI News 2010
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So the activation of RIG-I by free K63 polyubiquitin chains is a bit surprising -- but it's not the first time Chen's group has observed this strategy phenomenon.
HHMI News 2010
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"These K63 polyubiquitin chains are present in human cells, and likely all mammalian cells, and are extremely potent in activating RIG-I in this antiviral pathway," Chen said.
HHMI News 2010
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Cyt, cytochrome; Dyn IC, dynein intermediate chain; ADRP, adipose differentiation-related protein; Polyubq, polyubiquitin.
Naturejobs - All Jobs Marta Martinez-Vicente 2010
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The result is a polyubiquitin chain that is bound by the proteasome, allowing it to degrade the tagged protein
WN.com - Articles related to Scientists uncover mysterious workings of cholera bacteria 2010
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The result is a polyubiquitin chain that is bound by the proteasome, allowing it to degrade the tagged protein
WN.com - Articles related to Scientists uncover mysterious workings of cholera bacteria 2010
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The work described herein reveals a requisite role for Lys-269 (K269) for the rapid polyubiquitin-mediated degradation of cyclin D1.
Naturejobs - All Jobs O Barbash 2009
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The 26 S proteasome is an energy-dependent protease that degrades proteins modified with polyubiquitin chains.
Journal of Biological Chemistry current issue T. G. Gillette 2008
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Proc Natl A.ad Sci U S A. Thrower JS, Hoffman L, Rechsteiner M, Pickart CM (2000) Recognition of the polyubiquitin proteolytic signal.
PLoS ONE Alerts: New Articles Angela C. Poole et al. 2010
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