Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun biochemistry A
chain of severalubiquitin molecules attached to aprotein .
Etymologies
Sorry, no etymologies found.
Support
Help support Wordnik (and make this page ad-free) by adopting the word polyubiquitin.
Examples
-
"So now we have two examples showing that these free polyubiquitin chains can activate signaling cascades," said Chen.
-
So the activation of RIG-I by free K63 polyubiquitin chains is a bit surprising -- but it's not the first time Chen's group has observed this strategy phenomenon.
-
"These K63 polyubiquitin chains are present in human cells, and likely all mammalian cells, and are extremely potent in activating RIG-I in this antiviral pathway," Chen said.
-
Cyt, cytochrome; Dyn IC, dynein intermediate chain; ADRP, adipose differentiation-related protein; Polyubq, polyubiquitin.
-
The result is a polyubiquitin chain that is bound by the proteasome, allowing it to degrade the tagged protein
WN.com - Articles related to Scientists uncover mysterious workings of cholera bacteria
-
The result is a polyubiquitin chain that is bound by the proteasome, allowing it to degrade the tagged protein
WN.com - Articles related to Scientists uncover mysterious workings of cholera bacteria
-
The work described herein reveals a requisite role for Lys-269 (K269) for the rapid polyubiquitin-mediated degradation of cyclin D1.
-
The 26 S proteasome is an energy-dependent protease that degrades proteins modified with polyubiquitin chains.
-
Proc Natl A.ad Sci U S A. Thrower JS, Hoffman L, Rechsteiner M, Pickart CM (2000) Recognition of the polyubiquitin proteolytic signal.
Comments
Log in or sign up to get involved in the conversation. It's quick and easy.