from The American Heritage® Dictionary of the English Language, 4th Edition

  • n. A thickening or hardening of a body part, as of an artery, especially from excessive formation of fibrous interstitial tissue.
  • n. A disease characterized by this thickening or hardening.
  • n. Botany The hardening of cells by the formation of a secondary wall and the deposition of lignin.

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. The abnormal hardening of body tissues, such as an artery.

from the GNU version of the Collaborative International Dictionary of English

  • n. Induration; hardening; especially, that form of induration produced in an organ by increase of its interstitial connective tissue.
  • n. Hardening of the cell wall by lignification.

from The Century Dictionary and Cyclopedia

  • n. A hardening or induration; specifically, the increase of the sustentacular tissue (neuroglia, or connective tissue) of a part at the expense of the more active tissue.
  • n. In botany, the induration of a tissue or cell-wall either by thickening of the membranes or by their lignification (that is, by the formation of lignin in them).

from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.

  • n. any pathological hardening or thickening of tissue


Middle English sclirosis, from Medieval Latin sclīrōsis, from Greek sklērōsis, hardening, from sklēroun, to harden; see scleroma.
(American Heritage® Dictionary of the English Language, Fourth Edition)
From Ancient Greek σκλήρωσις (sklerosis, "an induration"), from *σκληροῦν (skleroyn, "to harden, indurate"), from σκληρός (skleros, "hard") (Wiktionary)



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