Definitions

from The American Heritage® Dictionary of the English Language, 5th Edition.

  • noun Enlargement of the spleen.

from The Century Dictionary.

  • noun Same as splenomegalia.

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun pathology An enlargement of the spleen.

from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.

  • noun an abnormal enlargement of the spleen

Etymologies

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Examples

  • · Single puncture, perpendicular to the abdomen, on a line joining the umbilicus and the anterior superior iliac spine, usually on the left, to avoid perforation of the cecum; on the right in the case of massive splenomegaly.

    Chapter 5 1989

  • Runt disease or splenomegaly (one of its earlier symptoms) provides a test of the immunological competence of cells, and lends itself to exact studies of their immunological capabilities; perhaps the most important discovery that can be credited to it is of the presence of an immunologically competent cell in peripheral blood.

    Peter Medawar - Nobel Lecture 1964

  • Of the 53 evaluable subjects who had splenomegaly at baseline

    unknown title 2011

  • In addition to demonstrating positive efficacy signals in the approvable endpoints in this indication, splenomegaly and symptomatic improvement, CYT387 also exhibited a promising ability to positively impact anemia, a major life-shortening symptom associated with myelofibrosis.

    unknown title 2011

  • These results were generally consistent with data reported previously at ASH 2010, demonstrating that CYT387 continues to display a favorable safety profile while meaningfully improving splenomegaly and constitutional symptoms.

    unknown title 2011

  • We describe the first case of CHF presenting in an otherwise healthy child, with thrombocytopenia and splenomegaly as the only manifestations of the disease.

    BioMed Central - Latest articles Serena Botto Poala 2010

  • Other notable findings at admission were splenomegaly, pancytopenia, hyponatremia, elevated levels of liver enzymes, hyperferritinemia and hypofibrinogenemia.

    Naturejobs - All Jobs Matthew P. Strout 2010

  • Patients were eligible to participate in the study if they presented with disease-related anemia and had at least one of the following clinical manifestations of Gaucher disease: thrombocytopenia, moderate splenomegaly or a readily palpable enlarged liver.

    RedOrbit News - Technology 2010

  • -- No, it's not a given that you'd develop splenomegaly but it IS the main complication that occurs in about half the people who get mono.

    Yahoo! Answers: Latest Questions 2010

  • (A) Representative images of spleen and lymph node of control (Ctrl) and N1N2K5 mice showing splenomegaly and lymphadenopathy (n = 12, three individual experiments).

    PLoS ONE Alerts: New Articles Alexis Dumortier et al. 2010

Comments

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  • Enlargement of the spleen. Wikipedia says it is often in response to "hyperfunction," something I definitely do not suffer from.

    September 21, 2007