Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun An
antidiabetic andantiinflammatory drug of thethiazolidinedione class.
Etymologies
Sorry, no etymologies found.
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Examples
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Medications such as troglitazone are used now to treat inflammatory diseases in adults, and we have demonstrated that these drugs have the ability to reverse the inflammatory effects of phthalates in white blood cells, "Weinberger said.
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Liver toxicity is a common problem of approved drugs that has led to recalls of high profile drugs such as troglitazone (Rezulin
Vitro Expands HemoGenix Alliance to Include Cell-based Testing for Liver Toxicity - Yahoo! Finance 2010
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Other drugs approved by the FDA and later found to cause harm include dexfenfluramine, a diet drug whose post-marketing data indicated an increased risk of pulmonary hypertension, and troglitazone, a diabetes drug that carried with it the risk of liver failure and was later pulled from the market.
John W. Whitehead: The Swine Flu or the FDA: Which Is More Dangerous to Your Health? 2009
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Furthermore, the 60% improvement in insulin sensitivity that results from vitamin D treatment indicates that that treatment is more potent than either troglitazone or metformin treatment 54% and 13% improvement in insulin sensitivity, respectively; 36.
More thoughts on why low-carb the second time around | The Blog of Michael R. Eades, M.D. 2009
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The diabetes medication troglitazone, better known as Rezulin, was tested on animals without significant problems, but caused liver damage in humans.
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The purpose of this study was to investigate whether troglitazone (TGZ) is considered as possible therapeutics in the treatment of growth and metastasis of osteosarcoma.
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In this study, we investigated the effects of troglitazone on the mRNA expression of VEGF and its receptors in NSCLC cell lines RERF-LC-AI, SK-MES-1, PC-14, and A549.
BioMed Central - Latest articles Takayuki Yoshizaki 2010
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In 2000, a related drug, Rezulin (troglitazone), was yanked from the market for causing liver failure (see 'Meet the
Scientific American 2010
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