Definitions
from The American Heritage® Dictionary of the English Language, 5th Edition.
- noun A sulfonylurea drug, C23H28ClN3O5S, used to treat non-insulin-dependent diabetes.
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun
Glibenclamide .
from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
- noun an oral antidiabetic drug (trade names DiaBeta and Micronase) that stimulates the release of insulin from the pancreas
Etymologies
from The American Heritage® Dictionary of the English Language, 4th Edition
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Examples
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Temporary withdrawal of glibenclamide, also known as glyburide, led to restoration of islet cell function in mice that had become glucose intolerant during continuous treatment with the sulfonylurea, Maria Sara Remedi, Ph. D., and Colin G. Nichols, Ph. D., of Washington University here, reported online in
MedPageToday.com - medical news plus CME for physicians 2008
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Medications for diabetes, such as glyburide (Glynase, Diabeta, Micronase) and glimepiride
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Metformin and sulfonylurea drugs -- the latter a class of diabetes drugs including glyburide, glipizide, chlorpropamide, tolbutamide and tolazamide -- are often among the first medications prescribed to lower blood sugar levels in people with type 2 diabetes.
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In addition, according to the FDA web site, significantly more female patients who received Avandia in the ADOPT study, "experienced fractures of the upper arm, hand, or foot, than did female patients who received either metformin or glyburide."
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Still more severe disease will require oral medications that encourage the pancreas to make more insulin such as glyburide or glipizide Some patients with even more severe type 2 disease are treated with subcutaneous injections of insulin.
CNN.com 2011
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Using records from primary care doctors, the researchers determined how many people in the pancreatic cancer and cancer-free groups had previously been diagnosed with diabetes and were on an anti-diabetes drug, such as metformin or sulfonylureas, which include glimepiride and glyburide.
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Drugs like glyburide, glimperide, etc. work by making your body release more insulin and can drop a diabetic's blood glucose fast.
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[1] Kahn SE, Haffner SM, Heise MA et al. Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy.
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