Definitions
from The American Heritage® Dictionary of the English Language, 5th Edition.
- noun The treatment of a medical disorder with a single drug.
- noun A type or instance of such treatment.
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun medicine A
therapy which is administered by itself
Etymologies
from Wiktionary, Creative Commons Attribution/Share-Alike License
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Examples
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Inactivin was intended to be used as short-term monotherapy, he said.
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Atrial fibrillation is less common among hypertensive patients taking long-term monotherapy with ACE inhibitors, angiotensin II-receptor blockers (ARBs), or beta-blockers than among those on calcium channel blockers, the
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Atrial fibrillation was less common if patients were on long-term monotherapy with ACE inhibitors (odds ratio, 0.77), ARBs (0.75), or beta-blockers (0.80), than if they were on calcium channel blockers.
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But the two new PMF cases involved patients taking it as "monotherapy," or with no other drug, as indicated on the Tysabri label.
Biogen, Elan Report 2008
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But four patients have now contracted PML when using Tysabri alone, suggesting the "monotherapy" rule may be less helpful than previously hoped.
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Tysabri was approved in the U.S. and EU primarily as a monotherapy a year later.
Drug Maker Elan Swings to Loss Sten Stovall 2010
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"We are pleased to provide data for patients with epilepsy who could benefit from Lyrica monotherapy in clinical practice," he said.
Pfizer Halts Lyrica Epilepsy Study, Cites Efficacy Peter Loftus 2011
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He declined to say whether Pfizer plans to seek regulatory approval for an epilepsy monotherapy indication for Lyrica.
Pfizer Halts Lyrica Epilepsy Study, Cites Efficacy Peter Loftus 2011
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Comparing combination antimicrobial therapy with monotherapy for the treatment of Acinetobacter baumannii, a major cause of bloodstream infection and pneumonia in health care settings
Antimicrobial Resistance: 8 Large NIH Trials Seek To Preserve The Usefulness Of Antibiotics NIH/NIAID 2010
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Comparing combination antimicrobial therapy with monotherapy for the treatment of Acinetobacter baumannii, a major cause of bloodstream infection and pneumonia in health care settings
Antimicrobial Resistance: 8 Large NIH Trials Seek To Preserve The Usefulness Of Antibiotics The Huffington Post News Team 2010
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