Definitions
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- verb To decrease the number of cell
receptors by usingdownregulation
Etymologies
Sorry, no etymologies found.
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Examples
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In particular, the researchers wanted to see whether the density of the receptors changes, because when dopamine is plentiful, dopamine receptors 'downregulate' - that is, move from the nerve-cell membrane to the inside of the cell, where they cannot be activated.
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They also downregulate enzymes that synthesize fat.
Forever Young M.D. Nicholas Perricone 2010
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Narbonne and Roy found that C. elegans larvae that lack a certain signaling pathway (the LKB1/AMPK pathway to be precise), which is activated during dauer, quickly downregulate fat mobilization so that lipid reserves are rationed to last the entire duration of the arrest.
Dr. Sharma’s Obesity Notes » Blog Archive » Fat-Burning Worms Key to Obesity Treatment? 2008
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Technically, it allows your brain to downregulate receptors and adapt to normal chemistry.
Dr. Alex Benzer: How to Toss Toxic Mates in 3 Simple Steps 2009
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Paradoxically, dramatically spiking caloric intake in this way once per week increases fat loss by ensuring that your metabolic rate thyroid function, etc. doesn't downregulate from extended caloric restriction.
More statin madness | The Blog of Michael R. Eades, M.D. 2009
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How long before your thryroid function, and other metabolic functions ‘downregulate?’
Intermittent fasting guest blog | The Blog of Michael R. Eades, M.D. 2008
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Paradoxically, dramatically spiking caloric intake in this way once per week increases fat loss by ensuring that your metabolic rate thyroid function, etc. doesn't downregulate from extended caloric restriction.
Low-carb diets reduce oxidative stress | The Blog of Michael R. Eades, M.D. 2008
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Insulin stays elevated and in a diabolical twist even stimulates more fat synthesis in the liver and tends to downregulate the insulin receptors, making them less responsive.
Changing dietary trends and the obesity epidemic | The Blog of Michael R. Eades, M.D. 2008
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If statins, which downregulate HGM-CoA reductase, also block CoQ10 production… does glucagon do something similar affect CoQ10?
Cholesterol and heart disease: no correlation | The Blog of Michael R. Eades, M.D. 2007
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This is so that your metabolism doesn't get used to a lower calorie load and downregulate itself.
unknown title 2011
hernesheir commented on the word downregulate
Quite the opposite of upregulate.
September 6, 2013
bilby commented on the word downregulate
Could be a sideregulate blown over by the wind.
September 6, 2013