hydroxyproline love


from the GNU version of the Collaborative International Dictionary of English.

  • noun A crystalline amino acid (C5H9NO3), a hydroxylated proline, obtained by hydrolysis of gelatin or collagen. Chemically it is 4-hydroxy-L-proline. It is classified as nonessential for growth in rats.

from Wiktionary, Creative Commons Attribution/Share-Alike License.

  • noun biochemistry A hydroxy derivative of the amino acid proline found in the structural proteins of connective tissue

from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.

  • noun a crystalline amino acid obtained from gelatin or collagen


Sorry, no etymologies found.


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  • On the presence of collagen in the brain of calf and man with special reference to the isolation of an unknown protein containing hydroxyproline by Leonard Wartofsky

    Solitary Confinement In U.S. Prisons Making Thousands Psychotic 2009

  • These animal express collagen, but it doesn't contain hydroxyproline.

    ScienceBlogs Channel : Life Science Nick Anthis none@example.com 2010

  • As a clarification of the above, molecular oxygen, as I understand it, is necessary for the post-transcriptional hydroxylation of proline to hydroxyproline - ie the oxygen in the hydroxyproline does not come from water, but is added from an O2 molecule by an oxygenase enzyme.

    ScienceBlogs Channel : Life Science Nick Anthis none@example.com 2010

  • Interestingly KGF levels correlated with hydroxyproline content of the lungs after bleomycin injury in controls but not in HSC-KGF treated mice (which we would have predicted to be lower due to the reduced injury), suggesting that the raised levels were indeed due to the local KGF delivery by bone marrow derived cells

    PLoS ONE Alerts: New Articles Susana Aguilar et al. 2009

  • The total collagen content of the left lung was determined by measuring hydroxyproline content in aliquots of pulverized left lung as described previously

    PLoS ONE Alerts: New Articles Susana Aguilar et al. 2009

  • • X-ray diffraction studies reveal a cylinder of water surrounding the triple-helix which is hydrogen-bonded to the hydroxyproline side-chains.

    Recently Uploaded Slideshows 2009

  • Almost one third of the amino acids are glycine and one quarter is proline or hydroxyproline.

    NutraIngredients-USA RSS 2009

  • In contrast, HPLC determination of hydroxyproline content, as a surrogate marker for collagen protein levels, demonstrated no significant differences between the bleomycin groups - in agreement with the Ashcroft scores.

    PLoS ONE Alerts: New Articles Susana Aguilar et al. 2009

  • Most of the polypeptide chain is a repeating unit of the tripeptide glycine-X-proline, where X is another amino acid and proline can be hydroxyproline.

    NutraIngredients-USA RSS 2009

  • Hydroxyproline was quantified by reverse-phase high performance liquid chromatography (HPLC) of 7-chloro-4-nitrobenzo-oxao-1,3, - diazole - ​ derived acid hydrolysates; the total left lung collagen was then calculated in milligrams, assuming that lung collagen contains 12. 2% (w/w) hydroxyproline.

    PLoS ONE Alerts: New Articles Susana Aguilar et al. 2009


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  • found exclusively in collagens.

    September 11, 2008

  • (and elastin? -- conflicting sources)

    September 11, 2008