Definitions
from The American Heritage® Dictionary of the English Language, 5th Edition.
- adjective Of, relating to, or activated by dopamine or related substances.
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- adjective Containing, involving, or transmitting
dopamine . - adjective Of or relating to
dopamine .
Etymologies
from The American Heritage® Dictionary of the English Language, 4th Edition
from Wiktionary, Creative Commons Attribution/Share-Alike License
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Examples
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The degeneration of these so-called dopaminergic nerve cells in the brain is a hallmark of Parkinson's.
PhysOrg.com - latest science and technology news stories 2010
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The degeneration of these so-called dopaminergic nerve cells in the brain is a hallmark of Parkinson's.
PhysOrg.com - latest science and technology news stories 2010
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He said the standard therapy, so-called dopaminergic drugs, had never been tested in pregnant women and might interfere with the baby's development or with milk production.
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Once within brain, neurons producing certain neurotransmitters, such as dopaminergic nigrostriatal cells, the excess phenylalanine can inhibit enzymes (like tyrosine hydroxylase) needed to synthesize the neurotransmitters.
Santa Fe Pediatrician Regales Hawaii Legislative Committee with Dangers of Aspartame 2008
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There is now evidence to support the notion that alterations in the dopaminergic reward system may be common to both ADD and hedonistic hyperphagia.
Dr. Sharma’s Obesity Notes » Blog Archive » Please Pay Attention - You May Have Obesity 2009
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"Changes in central dopaminergic systems with the expression of Shh or GDNF in mice perinatally exposed to bisphenol-A."
Sarah Janssen: BPA Ban in California Passes, Despite Industry Spin 2010
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George Ricaurte, a scientist working for the American Government investigated the effect of MDMA on dopaminergic neurones in the brains of monkeys.
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The role of stress in the pathophysiology of the dopaminergic system.
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The Journal of Clinical Endocrinology and Metabolism, has in a review article sponsored by the Endocrine Society, reported that "estrogen maintains functions of key neural structures, such as the hippocampus and basal forebrain, and the widely projecting dopaminergic, serotongenic, and noradrenergic systems."
T.S. Wiley: Estrogen Dilemma: There Is No Dilemma When You Know the Details T.S. Wiley 2010
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In one experiment Walsh and his team injected mice with a toxin, called MPTP, that induces Parkinson's disease by killing off dopaminergic neurons.
avivamagnolia commented on the word dopaminergic
A synapse is dopaminergic if it uses dopamine as its neurotransmitter. A substance is dopaminergic if it is capable of stimulating dopamine receptors in a dopaminergic synapse.
Dopaminergic nootropics include dopamine precursors and cofactors, agonists, MAOIs, and dopamine reuptake inhibitors:
* L-dopa - Prescription drug. Precursor to the neurotransmitter dopamine. Parkinson disease treatment.
* Phenylalanine (requires Vitamin B6 and Vitamin C) - Essential amino acid. Precursor to dopamine, stimulant, sleep reducer.
* Theanine - Found in tea. Increases serotonin, GABA and dopamine levels in the brain. Increases alpha-wave based alert relaxation.
* Tyrosine (requires Vitamin B6 and Vitamin C) - Amino acid. Precursor to dopamine, anti-depressant, sleep reducer.
* Vitamin C- improves cardiovascular elasticity and integrity, membrane stabilizer and major anti-oxidant (protects brain cells and prevents brain cell death), cofactor in the production of the neurotransmitters dopamine and serotonin.
* Vitamin B6 - co-factor used by the body to produce dopamine.
* Yohimbine - boosts dopamine levels through an unknown mechanism. Sometimes used as an aphrodisiac. Poses health risks: it is a neuro-paralytic which slows down breathing and induces acidosis, some symptoms of which are malaise, nausea, and vomiting. Contraindicated for users of megadoses of acidic vitamins or nutrients.citation needed
* MAOIs such as Selegiline which inhibits MAO-B (an enzyme that breaks down dopamine) thus raising dopamine by partially inhibiting its breakdown. (In large doses it also inhibits MAO-A)
* Tolcapone - Inhibits COMT (an enzyme that breaks down the neurotransmitters dopamine, epinephrine, and norepinephrine) and increases performance in tasks depending on working memory in individuals with a certain phenotype.
* Buproprion - atypical antidepressant, dopamine reuptake inhibitor.
* Dopamine agonists such as pergolide
January 18, 2009