from The American Heritage® Dictionary of the English Language, 4th Edition

  • n. A boy or man regarded as effeminate.
  • n. A person regarded as timid or cowardly.
  • n. Informal Sister.

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. An effeminate boy or man.
  • n. A timid, unassertive or cowardly person.
  • n. A male crossdresser who adopts feminine behaviours.
  • n. Sister.
  • n. Urination.
  • adj. Effeminate.
  • adj. Cowardly.


Diminutive of sis.
(American Heritage® Dictionary of the English Language, Fourth Edition)
Extended form of sis, from sister ("a female sibling") (Wiktionary)



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  • So what's the sense? pee?

    December 14, 2012

  • I've been watching a lot of "Dead Like Me" this week. In the first season there are at least two times when the charcter Rube (played by Mandy Patinkin) says he has to make a "sissy."

    December 13, 2012

  • (n): The eldest female child of a family.
    (synonym): Sister

    February 15, 2009

  • a sissy walks into a bar to grab on??????

    November 1, 2008