Definitions
from The American Heritage® Dictionary of the English Language, 5th Edition.
- noun Any of a group of enzymes that catalyze the synthesis of a compound.
from Wiktionary, Creative Commons Attribution/Share-Alike License.
- noun biochemistry Any
ligase thatsynthesizes biological compounds usingATP as a source of energy
Etymologies
from The American Heritage® Dictionary of the English Language, 4th Edition
from Wiktionary, Creative Commons Attribution/Share-Alike License
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Examples
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The synthetase is strongly inhibited by concentrations of citrate and FDP that are found in the brain suggesting a regulatory role of
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Islam, E, et al. Inhibition of rat brain prostaglandin D synthetase by 3-hydroxymethylglutamyl coenzyme reductase inhibitors.
T.S. Wiley: Estrogen Dilemma: There Is No Dilemma When You Know the Details T.S. Wiley 2010
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Aminoacyl-tRNA synthetase ribozyme, an example of the RNA-based catalysts that may have preceded protein enzymmes during the origin of life.
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Using data recently obtained from the emerging genome projects, our analysis points to the extant forms of lysyl-tRNA synthetase being preceded in evolution by the establishment of the identity of lysine tRNA.
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We present a phylogenetic analysis to determine whether a given tRNA molecule was established in evolution before its cognate aminoacyl-tRNA synthetase.
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Aminoacyl-tRNA synthetase ribozyme, an example of the RNA-based catalysts that may have preceded protein enzymmes during the origin of life.
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The earlier appearance of tRNA versus their metabolically related enzymes is a prediction of the RNA world theory, but the available synthetase and tRNA sequences previously had not allowed a formal comparison of their relative time of appearance.
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Secondary absence of mitochondria in Giardia lamblia and Trichomonas vaginalis revealed by valyl-tRNA synthetase phylogeny.
Parasite Rex Carl Zimmer 2009
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Why the need for two intermediate components – the synthetase and the tRNA?
Signature in the Cell: self-contradiction and repetition - The Panda's Thumb 2009
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Why the need for two intermediate components – the synthetase and the tRNA?
Signature in the Cell: self-contradiction and repetition - The Panda's Thumb 2009
dhuber commented on the word synthetase
An enzyme, a synthase. Also, a ligase.
September 25, 2008