from The American Heritage® Dictionary of the English Language, 4th Edition

  • n. A pathological condition of a part, organ, or system of an organism resulting from various causes, such as infection, genetic defect, or environmental stress, and characterized by an identifiable group of signs or symptoms.
  • n. A condition or tendency, as of society, regarded as abnormal and harmful.
  • n. Obsolete Lack of ease; trouble.

from Wiktionary, Creative Commons Attribution/Share-Alike License

  • n. An abnormal condition of the body or mind that causes discomfort or dysfunction; distinct from injury insofar as the latter is usually instantaneously acquired.
  • n. Any abnormal or harmful condition, as of society, people's attitudes, way of living etc.
  • v. To cause unease; to annoy, irritate.
  • v. To infect with a disease.

from the GNU version of the Collaborative International Dictionary of English

  • n. Lack of ease; uneasiness; trouble; vexation; disquiet.
  • n. An alteration in the state of the body or of some of its organs, interrupting or disturbing the performance of the vital functions, and causing or threatening pain and weakness; malady; affection; illness; sickness; disorder; -- applied figuratively to the mind, to the moral character and habits, to institutions, the state, etc.
  • transitive v. To deprive of ease; to disquiet; to trouble; to distress.
  • transitive v. To derange the vital functions of; to afflict with disease or sickness; to disorder; -- used almost exclusively in the participle diseased.

from The Century Dictionary and Cyclopedia

  • To make uneasy; pain; distress.
  • To affect with disease; make ill; disorder the body or mind of: used chiefly or only in the passive voice or the past participle.
  • n. Lack or absence of ease; uneasiness; pain; distress; trouble; discomfort.
  • n. In pathology: In general, a morbid, painful or otherwise distressing physical condition, acute or chronic, which may result either in death or in a more or loss complete return to health; deviation from the healthy or normal condition of any of the functions or tissues of the body.
  • n. Specifically— An individual case of such a morbid condition; the complex series of pathological conditions causally related to one another exhibited by one person during one period of illness; an attack of sickness.
  • n. A special class of morbid conditions grouped together as exhibiting the same or similar phenomena (symptoms, course, result), as affecting the same organs, or as due to the same causes: as, the diseases of the lungs, as pneumonia, consumption; the diseases of the brain.
  • n. Any disorder or depraved condition or element, moral, mental, social, or political.
  • n. Certain inflammatory conditions of joints attendant on locomotor ataxia.
  • n. See the adjectives.

from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.

  • n. an impairment of health or a condition of abnormal functioning


from The American Heritage® Dictionary of the English Language, 4th Edition

Middle English disese, from Old French : des-, dis- + aise, ease; see ease.

from Wiktionary, Creative Commons Attribution/Share-Alike License

Middle English disese, from Anglo-Norman desese, disaise, from Old French desaise (dis- +‎ ease). Displaced native Middle English adle, audle ("disease") (from Old English ādl ("disease, sickness")), Middle English cothe, coathe ("disease") (from Old English coþu ("disease")).


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